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Turki Turki, Sanjiban Sekhar Roy and Y.-H. Taguchi
It is difficult to identify histone modification from datasets that contain high-throughput sequencing data. Although multiple methods have been developed to identify histone modification, most of these methods are not specific to histone modification bu...
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Hyeonjin Cha, Jaeyoung Lee, Hee Ho Park and Ju Hyun Park
The generation of functional osteoblasts from human somatic cells could provide an alternative means of regenerative therapy for bone disorders such as osteoporosis. In this study, we demonstrated the direct phenotypic conversion of human dermal fibrobla...
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Aslihan Temel, Bianka Janack and Klaus Humbeck
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Xiaofang Zhang, Xiaodong Zhang, Bojun Yuan, Lijun Ren, Tianbao Zhang and Guocai Lu
Histone deacetylase inhibitors (HDACIs), such as vorinostat and panobinostat, have been shown to have active effects on many hematologic malignancies, including multiple myeloma and cutaneous T-cell lymphoma. Hydroxamate-based (Hb) HDACIs have very good ...
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Xiaodong Wang, Yuhang Guo, Yiru Wang, Yunling Peng, Hongwei Zhang and Jun Zheng
Drought stress presents a significant threat to the growth and development of maize. It is important to study the genes and mechanisms that contribute to drought tolerance. In this study, we identified ZmHDT103 (that encodes a histone deacetylase) by con...
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Rayanne H. N. Silva, Emanuel P. Magalhães, Rebeca C. Gomes, Yunierkis Perez-Castillo, Alice M. C. Martins and Damião P. de Sousa
Neglected tropical diseases (NTDs) cause thousands of deaths each year. Among these diseases, we find Chagas disease, whose etiologic agent is Trypanosoma cruzi. Piplartine is an alkamide present in various species of the genus Piper that possess trypano...
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Alexei V. Chernyshev and Neonila E. Polyakova
To date, a total of 23 valid species of heteronemerteans belonging to 15 genera have been recorded in Antarctic and Subantarctic waters. The ribbon worm Heteronemertes longifissa (Hubrecht, 1887) is the only heteronemertean species reported to have bipol...
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Ismael Khouly, Rosalie Salus Braun, Michelle Ordway, Iya Ghassib, Lena Larsson and Farah Asa?ad
The aims of this systematic review were to identify and synthesize the evidence for an association in DNA methylation/histone modifications between periodontal diseases and systemic diseases/smoking. Electronic database searches using relevant search ter...
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