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Coralia Cotoraci, Alciona Sasu, Eftimie Miutescu, Dana Iovanescu, Sami Gharbia, Alina Ciceu, Hildegard Herman and Anca Hermenean
Chemotherapy and radiation are often accompanied by complications such as intestinal mucositis. The aim of this study was to assess by immunohistochemical assay the consequences of epirubicin-based therapy applied to onco-hematological patients, on the m...
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Tan Ma, Xiaoqin Yin, Ruitong Han, Jie Ding, Huan Zhang, Xiaodong Han and Dongmei Li
Humans are inevitably exposed to ubiquitous phthalate esters (PAEs). In utero exposure to di-n-butyl phthalate (DBP) induces abnormal development of the testis and reproductive tract in male offspring, which correspond closely with the human condition of...
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Adina Pop Moldovan, Simona Dumitra, Cristina Popescu, Radu Lala, Nicoleta Zurbau Anghel, Daniel Nisulescu, Ariana Nicoras, Coralia Cotoraci, Monica Puticiu, Anca Hermenean and Daniela Teodora Marti
Anthracyclines, including epirubicin (Epi), are effective chemotherapeutics but are known for their cardiotoxic side effects, primarily inducing cardiomyocyte apoptosis. This study investigates the protective role of hesperetin (HSP) against cardiomyopat...
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Nazia Afroze, Sreepoorna Pramodh, Abdulmajeed G. Almutary, Tahir A. Rizvi, Naushad Rais, Ritu Raina, Md. Faiyazuddin, Abdullah M. Alnuqaydan and Arif Hussain
Kaempferol, a flavonoid, contains a plethora of therapeutic properties and has demonstrated its efficacy against cancer. This study aims to unravel the molecular targets that are being modulated by kaempferol on HeLa cells. Various assays were performed,...
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Hae-Jin Lee, Hae-Lim Kim, Dae-Young Lee, Dong-Ryung Lee, Bong-Keun Choi and Seung-Hwan Yang
We evaluated the effectiveness of Scrophularia buergeriana extract (Brainon) on cognitive dysfunction and determined its underlying mechanisms in a scopolamine (SCO)-treated mouse model of memory impairment. Brainon treatment for 28 days ameliorated the ...
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Jinnatun Nahar, Vinothini Boopathi, Esrat Jahan Rupa, Muhammad Awais, Anjali Kariyarath Valappil, Md Niaj Morshed, Mohanapriya Murugesan, Reshmi Akter, Dong Uk Yang, Ramya Mathiyalagan, Deok Chun Yang and Seok-Kyu Jung
The family Thymelaeaceae, which includes huge evergreen trees that are sparsely distributed in tropical rainforests, includes the genus Aquilaria. Numerous medical conditions, including inflammation, cancer, and oxidative stress have been traditionally t...
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Peramaiyan Rajendran, Hany Elsawy, Manal Alfwuaires and Azza Sedky
Plants from the family Brassicaceae produce brassinin (BSN), which is an essential indole phytoalexin. BSN can kill certain types of cancer cells. Using hepatocarcinoma (HCC) cells, we examined the molecular mechanisms of BSN. We found that HCC cell grow...
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Mohammed Al-Zharani, Fahd A. Nasr, Ali S. Alqahtani, Mary Anne W. Cordero, Amal A. Alotaibi, Asmatanzeem Bepari, Saud Alarifi, Ali Daoud, Ibrahim O. Barnawi and Haytham M. Daradka
Datura innoxia is an important species of Solanaceae family with several purposes in folk medicine. This study intends to explore the cytotoxic effect of D. innoxia on various cancer cell proliferation. D. innoxia ethanolic extract?s effect on the progre...
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Simona Ioana Vicas, Vasile Laslo, Adrian Vasile Timar, Cornel Balta, Hildegard Herman, Alina Ciceu, Sami Gharbia, Marcel Rosu, Bianca Mladin, Luminita Fritea, Simona Cavalu, Coralia Cotoraci, József Prokisch, Maria Puschita, Calin Pop, Eftimie Miutescu and Anca Hermenean
This paper demonstrates the ability of a functional food based on probiotics and selenium nanoparticles (SeNPs) to annihilate the toxic effect of cadmium on the kidneys. SeNPs were obtained by eco-friendly method used Lactobacillus casei. The morphologic...
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