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Fabio Cumbo, Eleonora Cappelli and Emanuel Weitschek
The recent advancements in cancer genomics have put under the spotlight DNA methylation, a genetic modification that regulates the functioning of the genome and whose modifications have an important role in tumorigenesis and tumor-suppression. Because of...
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Hanen Mhamdi, Jérémie Bourdon, Abdelhalim Larhlimi and Mourad Elloumi
The integration of high-throughput data to build predictive computational models of cellular metabolism is a major challenge of systems biology. These models are needed to predict cellular responses to genetic and environmental perturbations. Typically, ...
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Laura Orellana
At the very deepest molecular level, the mechanisms of life depend on the operation of proteins, the so-called ?workhorses? of the cell. Proteins are nanoscale machines that transform energy into useful cellular work, such as ion or nutrient transport, i...
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Baby Joseph,Ajisha S.U,Jeevitha M.V
Pág. 98 - 103
Abstract - RNA interference (RNAi) technology has become a novel tool for silencing gene expression in cells or organisms. RNA interference is the process that double-stranded RNA induces the homology-dependent degradation of cognate mRNA mediated by 21-...
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Petra Harsanyi, Kevin Scott, Blair A. A. Easton, Guadalupe de la Cruz Ortiz, Erica C. N. Chapman, Althea J. R. Piper, Corentine M. V. Rochas and Alastair R. Lyndon
Proposed offshore windfarm sites could overlap with the brooding and spawning habitats of commercially important crustacea, including European lobster, Homarus gammarus and Edible crab, Cancer pagurus. Concerns have been raised on the biological effects ...
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Sharifah Saffinas Syed Soffian, Azmawati Mohammed Nawi, Rozita Hod, Huan-Keat Chan and Muhammad Radzi Abu Hassan
The increasing pattern of colorectal cancer (CRC) in specific geographic region, compounded by interaction of multifactorial determinants, showed the tendency to cluster. The review aimed to identify and synthesize available evidence on clustering patter...
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Loai Abdallah, Murad Badarna, Waleed Khalifa and Malik Yousef
In the computational biology community there are many biological cases that are considered as multi-one-class classification problems. Examples include the classification of multiple tumor types, protein fold recognition and the molecular classification ...
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Robert Snyder
Excessive exposure to benzene has been known for more than a century to damage the bone marrow resulting in decreases in the numbers of circulating blood cells, and ultimately, aplastic anemia. Of more recent vintage has been the appreciation that an alt...
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