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Gloria Bellin, Chiara Gardin, Letizia Ferroni, Paolo Ghensi, Barbara Zavan and Marco Tatullo
Applied phytochemistry can improve the translational tissue engineering, by selective triggering of specific biological processes, ensuring a low impact on cell viability and the overall biocompatibility. Better knowledge of the synergic action of saponi...
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Venanzio Iacono, Simone Natali, Luca De Berardinis, Daniele Screpis, Antonio Pompilio Gigante and Claudio Zorzi
Introduction: The intra-articular injection of autologous micro-fragmented adipose tissue (MAT) is increasingly used to manage pain and dysfunction in subjects with osteoarthritis (OA). The purpose of this retrospective study was to report the safety and...
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Victoria Pulido-Escribano, Bárbara Torrecillas-Baena, Gabriel Dorado, María Ángeles Gálvez-Moreno, Marta Camacho-Cardenosa and Antonio Casado-Díaz
Hard-to-heal chronic wounds associated with aging and high-prevalence pathologies, such as diabetes, are a global health problem. Therefore, it is necessary to advance effective treatments to accelerate wound healing. Among these potential treatments are...
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Jia-Lin Wu, Pei-Chun Wong, Chung-Wei Ho, Chien-Han Chen, Kuan-Ya Liao, Ronald Lovel, Tang Bo-Chung Wu, Wen-Ying Chang, Yan-Zhang Lee and Willie Lin
The aim of this study is to evaluate the feasibility and usefulness of the human umbilical cord mesenchymal stem cells (hUC-MSCs) and hyaluronan acid (HA) combination to attenuate osteoarthritis progression in the knee while simultaneously providing some...
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Kosuke Morita, Jordy Schol, Tibo N. E. Volleman, Daisuke Sakai, Masato Sato and Masahiko Watanabe
Background: Multiple studies have examined the potential of growth factors (GF) to enable mesenchymal stromal cells (MSC) to nucleus pulposus (NP) cell-like cell differentiation. Here we screened a wide range of GF and GF combinations for supporting NP c...
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Delfo D?Alessandro, Stefania Moscato, Alessandra Fusco, Jose Gustavo De la Ossa, Mario D?Acunto, Luisa Trombi, Marta Feula, Lorenzo Pio Serino, Giovanna Donnarumma, Mario Petrini, Stefano Berrettini and Serena Danti
In this work, we provide a platform for nasal tissue regeneration, consisting of poly(vinyl alcohol)/gelatin sponges and mesodermal progenitor cells as a single stem cell source for connective and vascular tissues. These scaffolds show promise for applic...
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Jana Stepanovska, Roman Matejka, Martin Otahal, Jozef Rosina and Lucie Bacakova
The physical and chemical properties of the material surface, especially its roughness and wettability, have a crucial effect on the adhesion, proliferation, and differentiation of cells. The aim of this study is to select the most appropriate surface mo...
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Yuanyuan Li, Jia Guo, Shoulong Deng, Zili Gao, Yixun Liu and Qi Gu
Polycystic ovarian syndrome (PCOS) is a ubiquitous hormonal disorder and induces female infertility and heterogeneous syndromes, for which there is still no effective treatment. Thanks to the properties of immunomodulatory and endocrine regulation, mesen...
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Vuk Uskokovic
Despite decades of research into the interaction between cells and nanoparticles, there is a lack of consensus regarding how specific physicochemical characteristics of the nanoparticles, including chemical composition, crystallinity, size, morphology, c...
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Rahmetullah Varol, Gokhan Bora Esmer and Huseyin Uvet
A three-dimensional profile reconstruction of live cells in dynamic cell cultures is a challenging problem due to the highly scattering nature of cell mediums. Furthermore, it is an interesting problem since these cultures present the optimal in vitro co...
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Darina Bacenková, Marianna Trebunová, Luká? Zachar, Radovan Hudák, Gabriela I?aríková, Katarína ?urínová and Jozef ?ivcák
Mesenchymal stem cells (MSCs) represent a population of adherent cells that can be isolated from multiple adult tissues. MSCs have immunomodulatory capacity and the ability to differentiate into many cell lines. Research study examines the immunomodulato...
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Yung-Chieh Cho, Hsiao-Ting Huang, Wen-Chien Lan, Mao-Suan Huang, Takashi Saito, Bai-Hung Huang, Chi-Hsun Tsai, Fang-Yu Fan and Keng-Liang Ou
The potential application of the work is in the area of three-dimensional cell culture in vitro.
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Nobuyuki Ueda, Ikiru Atsuta, Yasunori Ayukawa, Takayoshi Yamaza, Akihiro Furuhashi, Ikue Narimatsu, Yuri Matsuura, Ryosuke Kondo, Yu Watanabe, Xiaoxu Zhang and Kiyoshi Koyano
We developed a remote administration method of Mesenchymal Stem Cells with therapeutic characteristic that used collagen gel as a scaffold.
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Masami Kanawa, Akira Igarashi, Katsumi Fujimoto, Veronica Sainik Ronald, Yukihito Higashi, Hidemi Kurihara, Yukio Kato and Takeshi Kawamoto
Mesenchymal stromal cells (MSCs) are a promising source for tissue engineering of soft connective tissues. However, the differentiation capacity of MSCs varies among individual cell lines. Here, we show marker genes to predict the adipogenic potential of...
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Shohei Ishikawa, Kazutoshi Iijima, Kohei Sasaki, Mineo Hashizume, Masaaki Kawabe and Hidenori Otsuka
In cartilage tissue engineering, three-dimensional (3D) scaffolds provide native extracellular matrix (ECM) environments that induce tissue ingrowth and ECM deposition for in vitro and in vivo tissue regeneration. In this report, we investigated 3D silic...
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Yaser A. Alhazmi, Mohammed Y. Aljabri, Shereen N. Raafat, Shaimaa M. Gomaa and Mohamed Shamel
Numerous tissue engineering uses for gingival-derived mesenchymal stem cells (GMSCs) have been demonstrated. Recently, low-level laser therapy (LLLT) has been projected as a factor that can improve MSCs? regeneration capacity. Therefore, the aim of this ...
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Griffin Rodgers, Guido R. Sigron, Christine Tanner, Simone E. Hieber, Felix Beckmann, Georg Schulz, Arnaud Scherberich, Claude Jaquiéry, Christoph Kunz and Bert Müller
Combining microtomography before and after decalcification with histology data by means of registration enables tri-variate histograms for labeling mature and newly formed bone as well as soft tissue components in rat jaw.
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Mike Wagenbrenner, Konrad Poker, Tizian Heinz, Marietta Herrmann, Konstantin Horas, Regina Ebert, Susanne Mayer-Wagner, Boris M. Holzapfel, Maximilian Rudert, Andre F. Steinert and Manuel Weißenberger
(1) Background: The mesenchymal stromal cells (MSCs) of different tissue origins are applied in cell-based chondrogenic regeneration. However, there is a lack of comparability determining the most suitable cell source for the tissue engineering (TE) of c...
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Chun-Ta Yu, Fu-Ming Wang, Yen-Ting Liu, Alvin Kai-Xing Lee, Tsung-Li Lin and Yi-Wen Chen
Cell-encapsulated bioscaffold is a promising and novel method to allow fabrication of live functional organs for tissue engineering and regenerative medicine. However, traditional fabrication methods of 3D scaffolds and cell-laden hydrogels still face ma...
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Pascal Ickrath, Martin Wagner, Agmal Scherzad, Thomas Gehrke, Marc Burghartz, Rudolf Hagen, Katrin Radeloff, Norbert Kleinsasser and Stephan Hackenberg
Zinc oxide nanoparticles (ZnO-NP) are widely spread in consumer products. Data about the toxicological characteristics of ZnO-NP is still under controversial discussion. The human skin is the most important organ concerning ZnO-NP exposure. Intact skin w...
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