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Angelo Iacobino, Lanfranco Fattorini and Federico Giannoni
This comprehensive overview of drug-resistant tuberculosis will be useful for researchers to expand their knowledge beyond mechanisms other than chromosomal mutations, and for the development of novel drugs/drug combinations, hoping to shorten the therap...
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Itumeleng H. Mabusa, Rachmond Howard, Peter Masoko
Pág. 8 bladsye
Sutherlandia frutescens (L) R. Br. contains several essential, bioactive compounds with clinically proven pharmacological activities. Sutherlandia is prescribed for people with tuberculosis but it is still not known what compounds in this plant...
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Balachandra Bandodkar, Radha Krishan Shandil, Jagadeesh Bhat and Tanjore S. Balganesh
After several years of limited success, an effective regimen for the treatment of both drug-sensitive and multiple-drug-resistant tuberculosis is in place. However, this success is still incomplete, as we need several more novel combinations to treat ext...
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Aaron Goff, Daire Cantillon, Leticia Muraro Wildner and Simon J Waddell
Multi-omics strategies are indispensable tools in the search for new anti-tuberculosis drugs. Omics methodologies, where the ensemble of a class of biological molecules are measured and evaluated together, enable drug discovery programs to answer two fun...
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Zhezhe Cui, Dingwen Lin, Virasakdi Chongsuvivatwong, Edward A. Graviss, Angkana Chaiprasert, Prasit Palittapongarnpim, Mei Lin, Jing Ou and Jinming Zhao
The aims of the study were: (1) compare sociodemographic characteristics among active tuberculosis (TB) cases and their household contacts in cold and hot spot transmission areas, and (2) quantify the influence of locality, genotype and potential determi...
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Terezinha Aparecida Guedes, Ana Beatriz Tozzo Martins, Isolde Terezinha Santos Previdelli (Author)
Pág. 511 - 514
Multivariate analysis or more specifically simple correspondence analysis was applied to verify the associations between variables present in tuberculosis occurrences. The results led to the conclusion that the great majority of tuberculosis (Mycobacteri...
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Terezinha Aparecida Guedes, Ana Beatriz Tozzo Martins, Isolde Terezinha Santos Previdelli
Pág. 511 - 514
Neste estudo, procurou-se, através da aplicação da análise multivariada, mais precisamente, análise de correspondência simples, estabelecer associações entre as variáveis presentes na ocorrência de tuberculose. Conclui-se que, para o grupo em estudo, a m...
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Giulia Degiacomi, Juan Manuel Belardinelli, Maria Rosalia Pasca, Edda De Rossi, Giovanna Riccardi and Laurent Roberto Chiarelli
The development and spread of Mycobacterium tuberculosis multi-drug resistant strains still represent a great global health threat, leading to an urgent need for novel anti-tuberculosis drugs. Indeed, in the last years, several efforts have been made in ...
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Carlos Martin, Nacho Aguilo, Dessislava Marinova and Jesus Gonzalo-Asensio
In addition to antibiotics, vaccination is considered among the most efficacious methods in the control and the potential eradication of infectious diseases. New safe and effective vaccines against tuberculosis (TB) could be a very important tool and are...
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Samiyah K. Al-Shammari, Doha M. Al-Nouri, Shaista Arzoo and Laila Naif Al-Harbi
This study evaluated the protective effect of different dietary ?-6/?-3 ratios in oils obtained from various nuts (walnut, peanut, cashew, and hazelnut) against morphological features and markers of inflammation on an adjuvant-induced arthritis rat model...
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Maicon Herverton Lino Ferreira da Silva Barros, Geovanne Oliveira Alves, Lubnnia Morais Florêncio Souza, Elisson da Silva Rocha, João Fausto Lorenzato de Oliveira, Theo Lynn, Vanderson Sampaio and Patricia Takako Endo
Tuberculosis (TB) is an airborne infectious disease caused by organisms in the Mycobacterium tuberculosis (Mtb) complex. In many low and middle-income countries, TB remains a major cause of morbidity and mortality. Once a patient has been diagnosed with ...
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Simeone Marino and Denise E. Kirschner
Tuberculosis (TB) is a world-wide health problem with approximately 2 billion people infected with Mycobacterium tuberculosis (Mtb, the causative bacterium of TB). The pathologic hallmark of Mtb infection in humans and Non-Human Primates (NHPs) is the fo...
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Itumeleng H. Mabusa, Rachmond Howard, Peter Masoko
Pág. 8 bladsye
Sutherlandia frutescens (L) R. Br. bevat verskeie essensiële bioaktiewe verbindings met farmakologiese aktiwiteit waarvoor daar kliniese bewyse bestaan. Sutherlandia word vir mense met tuberkulose voorgeskryf, maar niemand weet nog watter verbi...
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