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Andrew K.H. Robertson, Andrew Lobbezoo, Louis Moskven, Paul Schaffer and Cornelia Hoehr
With recent impressive clinical results of targeted alpha therapy using 225Ac, significant effort has been directed towards providing a reliable and sufficient supply of 225Ac to enable widespread using of 225Ac-radiopharmaceuticals. TRIUMF has begun pro...
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Petra Otevrelová and Barbora Brodská
Survivin is a 16.5 kDa protein highly expressed in centrosomes, where it controls proper sister chromatid separation. In addition to its function in mitosis, survivin is also involved in apoptosis. Overexpression of survivin in many cancer types makes it...
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Claudia Cannas, Benedetta Pintus, Lina Corgiolu, Enrico Borrelli, Giacomo Boscia, Mario Damiano Toro and Giuseppe Giannaccare
The present article provides an overview of photobiomodulation (PBM), also known as low-level laser light therapy (LLLT), which has garnered attention in ophthalmology for its potential therapeutic benefits in various ocular diseases. Photobiomodulation ...
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Cosmin Trif, Dragos Paul Mihai, Anca Zanfirescu and George Mihai Nitulescu
The fatty acid amide hydrolase (FAAH) is an enzyme responsible for the degradation of anandamide, an endocannabinoid. Pharmacologically blocking this target can lead to anxiolytic effects; therefore, new inhibitors can improve therapy in this field. In o...
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Andreea Nedelcu, Ofelia Mosteanu, Teodora Pop, Teodora Mocan and Lucian Mocan
There have been continuous advances in nanoscience since the beginning of the 21st century, and the emerging field of computational nanomedicine, the development of nanomaterial-based sensors or the prominent biomedical engineering applications should be...
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Vu Hoang Minh Doan, Van Tu Nguyen, Jaeyeop Choi, Sumin Park and Junghwan Oh
The objective of this study is to design a therapeutic method combining a portable high intensity focused ultrasound (HIFU) design which is suitable for the laboratory environment and a tailored integrated photo-acoustic imaging (PAI) system for monitori...
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Kazuhiro Nouso, Takamasa Ohki, Tatsuya Yamashita, Haruyuki Takaki, Chien-Au Liu, Tae Wook Kang, Dong Ho Lee, So Jung Lee, Suyash Kulkarni, Deepa Shree and Masatoshi Tanaka
Many guidelines and standard therapies have been published for the treatment of hepatocellular carcinoma (HCC). Multiple options for the treatment of early to intermediate-stage HCC have resulted in several differences between the guidelines. In addition...
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Saverio Braccini and Francisco Alves
The 17th Workshop on Targets and Target Chemistry (WTTC17) was held in Coimbra (Portugal) on 27?31 August 2018. A few months before, the 13th Workshop of the European Cyclotron Network (CYCLEUR) took place in Lisbon (Portugal) on 23?24 November 2017. The...
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Baby Joseph,Ajisha S.U,Jeevitha M.V
Pág. 98 - 103
Abstract - RNA interference (RNAi) technology has become a novel tool for silencing gene expression in cells or organisms. RNA interference is the process that double-stranded RNA induces the homology-dependent degradation of cognate mRNA mediated by 21-...
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Sufyan Danish, Asfandyar Khan, L. Minh Dang, Mohammed Alonazi, Sultan Alanazi, Hyoung-Kyu Song and Hyeonjoon Moon
Bioinformatics and genomics are driving a healthcare revolution, particularly in the domain of drug discovery for anticancer peptides (ACPs). The integration of artificial intelligence (AI) has transformed healthcare, enabling personalized and immersive ...
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Lennart Volz, Claire-Anne Reidel, Marco Durante, Yolanda Prezado, Christoph Schuy, Uli Weber and Christian Graeff
Particle minibeam therapy has demonstrated the potential for better healthy tissue sparing due to spatial fractionation of the delivered dose. Especially for heavy ions, the spatial fractionation could enhance the already favorable differential biologica...
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Haoyang Wang, Yuchen Sun, Yuxin Wang, Ying Chen, Yun Ge, Jie Yuan and Paul Carson
Hyperthermia therapy (HT) is used to treat diseases through heating of high temperature usually in conjunction with some other medical therapeutics such as chemotherapy and radiotherapy. In this study, we propose a promising temperature-controlled hypert...
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Sarah Parkinson, Sophie Schumann, Amelia Taylor, Clare Fenton, Gavin Kearney, Megan Garside and Daniel Johnston
Previous studies have shown that autistic people often display atypical responses when processing sensory information, with particular prevalence within the auditory domain. Often provoked by common everyday sounds, auditory hypersensitivity can result i...
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Andrew Carter, Seth Racey and Stephany Veuger
Iron is a key metal involved in several biological processes such as DNA replication and repair, cellular proliferation and cell cycle regulation. Excess volumes of labile iron are toxic and can lead to the production of ROS (reactive oxygen species) via...
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Ghaida Albakri, Rahma Bouaziz, Wallaa Alharthi, Slim Kammoun, Mohammed Al-Sarem, Faisal Saeed and Mohammed Hadwan
A specific phobia is a common anxiety-related disorder that can be treated efficiently using different therapies including exposure therapy or cognitive therapy. One of the most famous methods to treat a specific phobia is exposure therapy. Exposure ther...
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Jason Corburn, Yael Nidam and Amanda Fukutome-Lopez
Urban gun violence is a critical human health and social justice issue. Strategies to reduce urban gun violence are increasingly being taken out of the domain of police and into community-based programs. One such community-driven gun violence reduction p...
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Mukesh Soni, Tissa Wijeratne and David Ackland
Video and music as a dissociative attention stimulus during exercise is known to distract from the discomfort of physical exertion and improve exercise adherence; however, the influence of video-based feedback and engagement during pedalling on the perfo...
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Konstantin A. Koshechkin, Georgiy S. Lebedev, Eduard N. Fartushnyi and Yuriy L. Orlov
Recent developments in Digital Medicine approaches concern pharmaceutical product optimization. Artificial Intelligence (AI) has multiple applications for pharmaceutical products? lifecycle, increasing development speed, quality of the products, and effi...
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Zhannat Ashikbayeva, Arman Aitkulov, Alexey Wolf, Alexander Dostovalov, Aida Amantayeva, Aliya Kurbanova, Vassilis J. Inglezakis and Daniele Tosi
Thermal ablation (TA) is known as an alternative therapy to surgery to treat tumors. However, TA-based therapy requires advanced approaches in order to prevent causing damage to healthy tissue around the tumor and selectively target the desired area. Nan...
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Jordan J. Becker, Tara L. McIsaac, Shawn L. Copeland and Rajal G. Cohen
Background: Alexander technique private lessons have been shown to reduce chronic neck pain and are thought to work by different mechanisms than exercise. Group classes may also be effective and would be cost-effective. Design: A two-group pre-test/post-...
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