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Sónia Claúdia Ribeiro, Rúben Fernandes, Felismina T. C. Moreira and Maria Goreti Ferreira Sales
This paper presents a potentiometric biosensor for the detection of amyloid ß-42 (Aß-42) in point-of-care analysis. This approach is based on the molecular imprint polymer (MIP) technique, which uses covalently immobilised Aß-42 to create specific detect...
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Miey Park, So-Hyeun Kim and Hae-Jeung Lee
Alzheimer?s disease (AD) is a neurodegenerative disorder characterized by the accumulation of ß-amyloid plaques and hyperphosphorylated tau proteins in the brain. Cell signaling pathways such as PI3K/Akt are known to play an essential role in regulating ...
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Nicola Gaetano Gatta, Andrea Parente, Francesca Guida, Sabatino Maione and Vittorio Gentile
Background: Tissue type 2 transglutaminase (TG2, E.C. 2.3.2,13) is reported to be involved in the phagocytosis of apoptotic cells in mouse microglial BV2 cells and peripheral macrophages. In this study, by using lipopolysaccharide (LPS)- or amyloid-ß 1-4...
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Iuliana Hunea, Laura Riscanu, Nona Girlescu, Madalina Diac, Anton Knieling, Sofia David, Cristina Furnica, Codrin Lucasevici, Irina Catrinel Dragomir, Diana Bulgaru Iliescu and Manuela Ciocoiu
Traumatic brain injury (TBI) is one of the leading causes of death worldwide, particularly in young people. Diffuse axonal injuries (DAI) are the result of strong rotational and translational forces on the brain parenchyma, leading to cerebral oedema and...
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