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Marianna Capecci, Nicolò Baldini, Francesca Campignoli, Lorenzo Pasquale Lombardo, Elisa Andrenelli and Maria Gabriella Ceravolo
The COVID-19 pandemic has been a stress test for the population, especially for people with chronic disorders such as Parkinson?s disease (PD). In addition to public health restrictions that contrast with PD management recommendations, there were deep ch...
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Jigishu Ahmed, Hafizur Rahman
Pág. 38 - 46
Alzheimer?s disease is one form of dementia affecting a significant proportion of the population. The etiology of this prevalent disease is currently unknown. It is postulated that AD can be treated by using stem cell-based therapies by replacing the los...
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Gennaro Vessio
Studying the effects of neurodegeneration on handwriting has emerged as an interdisciplinary research topic and has attracted considerable interest from psychologists to neuroscientists and from physicians to computer scientists. The complexity of handwr...
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Stephen C. Bondy
This review explores the processes underlying the deleterious effects of the presence of insoluble or colloidal depositions within the central nervous system. These materials are chemically unreactive and can have a prolonged residence in the brain. They...
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Maria Dyah Nur Meinita, Dicky Harwanto and Jae-Suk Choi
Seaweeds or marine macroalgae are known for producing potentially bioactive substances that exhibit a wide range of nutritional, therapeutic, and nutraceutical properties. These compounds can be applied to treat chronic diseases, such as cancer, cardiova...
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Pratham Grover, Kunal Chaturvedi, Xing Zi, Amit Saxena, Shiv Prakash, Tony Jan and Mukesh Prasad
Alzheimer?s disease is a chronic neurodegenerative disease that causes brain cells to degenerate, resulting in decreased physical and mental abilities and, in severe cases, permanent memory loss. It is considered as the most common and fatal form of deme...
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Miranda Bellezza, Azzurra di Palma and Andrea Frosini
Alzheimer?s disease (AD) is a neurodegenerative disorder that leads to the loss of cognitive functions due to the deterioration of brain tissue. Current diagnostic methods are often invasive or costly, limiting their widespread use. Developing non-invasi...
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Artur Chudzik and Andrzej W. Przybyszewski
Neurodegenerative diseases (NDs), including Parkinson?s and Alzheimer?s disease, pose a significant challenge to global health, and early detection tools are crucial for effective intervention. The adaptation of online screening forms and machine learnin...
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Juan Jiang, Hong Liu, Xin Yu, Jin Zhang, Bing Xiong and Lidan Kuang
Precisely segmenting the hippocampus from the brain is crucial for diagnosing neurodegenerative illnesses such as Alzheimer?s disease, depression, etc. In this research, we propose an enhanced hippocampus segmentation algorithm based on 3D U-Net that can...
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Zhiqiong Wang, Zican Lin, Shuo Li, Yibo Wang, Weiying Zhong, Xinlei Wang and Junchang Xin
Alzheimer?s disease (AD) is a progressive, irreversible neurodegenerative disorder that requires early diagnosis for timely treatment. Functional magnetic resonance imaging (fMRI) is a non-invasive neuroimaging technique for detecting brain activity. To ...
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Zeyuan Zhao, Ping Li, Yongjie Dai, Zhaoe Min and Lei Chen
Alzheimer?s disease (AD) is an irreversible neurodegenerative disease. Providing trustworthy AD progression predictions for at-risk individuals contributes to early identification of AD patients and holds significant value in discovering effective treatm...
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Diletta Piatti, Riccardo Marconi, Giovanni Caprioli, Simone Angeloni, Massimo Ricciutelli, Gokhan Zengin, Filippo Maggi, Luca Pagni and Gianni Sagratini
This study assessed the impact of full and late flowering stages on the polyphenols and enzyme inhibitory properties of Hypericum perforatum from Poland. Recognizing the significance of phenolic compounds in disease prevention and melatonin?s emerging pr...
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Rodrigo Olivares, Roberto Munoz, Ricardo Soto, Broderick Crawford, Diego Cárdenas, Aarón Ponce and Carla Taramasco
During the last years, highly-recognized computational intelligence techniques have been proposed to treat classification problems. These automatic learning approaches lead to the most recent researches because they exhibit outstanding results. Neverthel...
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Lin Tan, Suxia Guo, Funing Ma, Chen Chang and Isabel Gómez-Betancur
Acetylcholinesterase is one of the most important enzymes in living organisms, which is responsible for the synapse cholinergic and other nervous processes. However, its inhibiting effects have proven to have pharmacological applications in the treatment...
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Runako M. Katsidzira, Mietha M. van der Walt, Jacobus J. Bergh, Gisella Terre?Blanche
Pág. 7 bladsye
Parkinson?s disease is a complex neurodegenerative condition with current treatment only focussed on symptomatic therapy that does not slow or stop the progression of the disease. Since the discovery that adenosine A1 and A2A receptors are potential...
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Zhaoyi Chen, Yuchen Yang, Dazheng Zhang, Jingchuan Guo, Yi Guo, Xia Hu, Yong Chen and Jiang Bian
Alzheimer?s disease (AD) and AD-related dementias (AD/ADRD) are a group of progressive neurodegenerative diseases. The progression of AD can be conceptualized as a continuum in which patients progress from normal cognition to preclinical AD (i.e., no sym...
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Luciana Rigoli, Valerio Caruso, Concetta Aloi, Alessandro Salina, Mohamad Maghnie, Giuseppe d'Annunzio, Olga Lamacchia, Giuseppina Salzano, Fortunato Lombardo and Giuseppe Picca
Wolfram syndrome 1, a rare autosomal recessive neurodegenerative disease, is caused by mutations in the WFS1 gene. It is characterized by diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (DIDMOAD), and other clinical manifestations such...
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Alessia Sarica, Maria Grazia Vaccaro, Andrea Quattrone and Aldo Quattrone
Cluster analysis is widely applied in the neuropsychological field for exploring patterns in cognitive profiles, but traditional hierarchical and non-hierarchical approaches could be often poorly effective or even inapplicable on certain type of data. Mo...
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Miey Park, So-Hyeun Kim and Hae-Jeung Lee
Alzheimer?s disease (AD) is a neurodegenerative disorder characterized by the accumulation of ß-amyloid plaques and hyperphosphorylated tau proteins in the brain. Cell signaling pathways such as PI3K/Akt are known to play an essential role in regulating ...
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Omid Bazgir, Eric Walden, Brian Nutter and Sunanda Mitra
Developing tools for precise quantification of brain metabolites using magnetic resonance spectroscopy (MRS) is an active area of research with broad application in non-invasive neurodegenerative disease studies. The tools are mainly developed based on b...
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