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Máté Siket, György Eigner, Dániel András Drexler, Imre Rudas and Levente Kovács
One challenging aspect of therapy optimization and application of control algorithms in the field of tumor growth modeling is the limited number of measurable physiological signals?state variables?and the knowledge of model parameters. A possible solutio...
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Winter Sinkala and Tembinkosi F. Nkalashe
Two equations are considered in this paper?the Black?Scholes equation and an equation that models the spatial dynamics of a brain tumor under some treatment regime. We shall call the latter equation the tumor equation. The Black?Scholes and tumor equatio...
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Bence Czakó and Levente Kovács
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Samuel Ruiz-Arrebola, Damián Guirado, Mercedes Villalobos and Antonio M. Lallena
The analysis carried out has shown that the Gompertz model has the best predictive capabilities concerning the tumor growth. This model should substitute the exponential one in clinical practice.
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Romina Mancinelli, Caterina Loredana Mammola, Roberta Sferra, Simona Pompili, Antonella Vetuschi and Luigi Pannarale
Angiogenesis plays a fundamental role in tumor growth and progression. It is regulated by several growth factors, including vascular endothelial growth factor protein family (VEGF) and its receptors, which are probably the most important factors responsi...
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Wendel Mattos Pompilho, Franz Viana Borges, Emilio de Castro Miguel
Cancer main feature is the abnormal, diffuse and uncontroled cell growth. It is the major cause of mortality all over the world and, in this context, every day the number of papers reporting the importance of screening pharmacologically active ...
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Wendel Mattos Pompilho, Franz Viana Borges, Emilio de Castro Miguel
Cancer main feature is the abnormal, diffuse and uncontroled cell growth. It is the major cause of mortality all over the world and, in this context, every day the number of papers reporting the importance of screening pharmacologically active ...
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Qing Gao, Daiwen Chen, Xuemei Ding, Zhiwen Xu, Aimin Wu and Keying Zhang
In order to study the effects of dietary folic acid (FA) supplementation on growth performance and immune status in weanling piglets, a single factorial randomized block design trial was conducted with six diets supplemented with FA at 0, 0.30, 3.00, 6.0...
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Po-Tsang Lee, Yu-Sheng Wu, Chung-Chih Tseng, Jia-Yu Lu and Meng-Chou Lee
This study evaluated the effects of the feeding of spent mushroom substrate from Agaricus blazei on Nile tilapia (Oreochromis niloticus). The safety of 0?1000 µg/mL A. blazei spent substrate water extract (ABSSE) was demonstrated in the primary hepatic a...
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Giampaolo D?Alessandro, Pantea Tavakolian and Stefano Sfarra
The present review aims to analyze the application of infrared thermal imaging, aided by bio-heat models, as a tool for the diagnosis of skin and breast cancers. The state of the art of the related technical procedures, bio-heat transfer modeling, and th...
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Elias Dritsas and Maria Trigka
The lungs are the center of breath control and ensure that every cell in the body receives oxygen. At the same time, they filter the air to prevent the entry of useless substances and germs into the body. The human body has specially designed defence mec...
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Bárbara Costa, Rita Matos, Irina Amorim, Fátima Gärtner and Nuno Vale
The breast cancer therapies available are insufficient, especially since first-line treatments, such as paclitaxel, result in drug resistance and their toxicity often limits their concentration. Strategies like drug repurposing are beneficial, and novel ...
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Hiroto Fujita, Yuka Kataoka and Masayasu Kuwahara
We have previously developed a bifunctional aptamer (bApt) binding to both human thrombin and camptothecin derivative (CPT1), and showed that bApt acts as a drug carrier under the phenomenon named selective oligonucleotide entrapment in fibrin polymers (...
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Claudio Luparello, Debora Ragona, Dalia Maria Lucia Asaro, Valentina Lazzara, Federica Affranchi, Vincenzo Arizza and Mirella Vazzana
Triple-negative breast cancer (TNBC) is a highly malignant tumor histotype which lacks effective targeted therapies, thereby being considered as the most aggressive form of breast carcinoma. To identify novel compounds which could counteract TNBC cell gr...
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Marcia Kamogae, Elisa Yoko Hirooka (Author)
Pág. 1189 - 1200
Population growth allied with the modernization of society has increased water consumption and transformed reservoirs into indispensable sources of water supply. Several interrelated factors, conspicuously microcystins, have contributed to aggravate the ...
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Kai Qiu, Zhimin Chen, Aijuan Zheng, Wenhuan Chang, Huiyi Cai, Xin Zhang and Guohua Liu
This study aimed to disclose the effects of a new compound organic acidifier mixing with L-malic acid and L-lactic acid on broiler production. A total of 1000 1-day-old Arbor acres broiler chicks were randomly divided into two treatments of 10 replicates...
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Ayesha Younis, Li Qiang, Charles Okanda Nyatega, Mohammed Jajere Adamu and Halima Bello Kawuwa
A brain tumor is a distorted tissue wherein cells replicate rapidly and indefinitely, with no control over tumor growth. Deep learning has been argued to have the potential to overcome the challenges associated with detecting and intervening in brain tum...
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Peramaiyan Rajendran, Hany Elsawy, Manal Alfwuaires and Azza Sedky
Plants from the family Brassicaceae produce brassinin (BSN), which is an essential indole phytoalexin. BSN can kill certain types of cancer cells. Using hepatocarcinoma (HCC) cells, we examined the molecular mechanisms of BSN. We found that HCC cell grow...
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Melania Gaggini, Cristina Vassalle, Fabrizia Carli, Maristella Maltinti, Laura Sabatino, Emma Buzzigoli, Francesca Mastorci, Francesco Sbrana, Amalia Gastaldelli and Alessandro Pingitore
Background: Exercise may affect lipid profile which in turn is related to inflammation, although changes of ceramides, diacylglycerols-DAG and sphingomyelin-SM and their relationship with inflammatory parameters following a half-marathon have never been ...
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Ramona Gabriela Ursu, Simona Eliza Giusca, Irene Alexandra Spiridon, Bianca Manole, Mihai Danciu, Victor Vlad Costan, Dragos Octavian Palade, Nicolae Ghetu, Paula Toader, Madalina Alexandra Vlad, Costin Damian, Elena Porumb-Andrese, Ionut Luchian and Lumini?a Smaranda Iancu
Background: Human papilloma virus (HPV) is acknowledged as a risk factor for oropharyngeal squamous cellular cancers (OPSCC), of which the dominant types are tonsillar (TSCC) and base of tongue cancer (BOTSCC). Objective: To assess the role of HPV in sel...
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