Resumen
Protein kinase C (PKC) isozymes play key roles in the proliferation, differentiation, survival, migration, invasion, apoptosis, and anticancer drug resistance of cancer cells. PKC isozymes are attractive therapeutic targets for cancer and have great potential as diagnostic and prognostic biomarkers for diagnosing cancers and for predicting disease-free survival and survival rates, respectively. This review discusses the potential of PKC isozymes as diagnostic and prognostic biomarkers and therapeutic targets for cancer.