Resumen
Bladder cancer (BC) is one of the most frequent cancers in the world and the urological tumor that presents the highest mortality. The diagnostic and prognostic methods available at present for BC are expensive and highly invasive for the patient, so the pursue of biomarkers that may replace those methods has been ongoing for years with limited success. One of these potential biomarkers is cell-free DNA, which can be found in liquid biopsies such as urine and blood. The present review summarizes the most recent research findings in the study of cell-free DNA to diagnose BC and even monitor treatment.