Inicio  /  Cancers  /  Vol: 14 Par: 21 (2022)  /  Artículo
ARTÍCULO
TITULO

Identification of MYEOV-Associated Gene Network as a Potential Therapeutic Target in Pancreatic Cancer

Yu Chen    
Jialun Wang    
Qiyuan Guo    
Xihan Li and Xiaoping Zou    

Resumen

Exploring the key molecular regulatory mechanism of pancreatic cancer is crucial to investigate the therapeutic strategies for pancreatic cancer. To precisely identify key pancreatic cancer genes, we used a multiple analyses integrated approach. We performed gene association analysis on the key gene MYEOV we discovered, which led to a molecular network with MYEOV as the core. The genes in this molecular network could work together to influence the development of pancreatic cancer, possibly through protumor immune cell infiltration. It is the first report to focus on the possibility that MYEOV may act as a ceRNA to form an interaction network with some pancreatic cancer-related genes such as KRAS and serve as a strategic therapeutic target of pancreatic cancer treatment.

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