Inicio  /  Cancers  /  Vol: 14 Par: 21 (2022)  /  Artículo
ARTÍCULO
TITULO

Protein Arginine Methyltransferases as Therapeutic Targets in Hematological Malignancies

Camille Sauter    
John Simonet    
Fabien Guidez    
Baptiste Dumétier    
Baptiste Pernon    
Mary Callanan    
Jean-Noël Bastie    
Romain Aucagne and Laurent Delva    

Resumen

This review summarizes the current findings about the cellular roles of protein arginine methyltransferases (PRMTs) in the formation of blood cells from stem cell progenitors and in different blood cancers such as leukemia and lymphoma. The work also provides a substantial insight into the development and the use of PRMT inhibitors for the treatment of hematological cancers. This review aims to show the research community that targeting PRMTs could be a novel and promising therapeutic approach for these diseases.

PÁGINAS
pp. 0 - 0
REVISTAS SIMILARES

 Artículos similares