Resumen
Background: Digital breast tomosynthesis (DBT) systems employ a sophisticated set of acquisition parameters to generate an image set, and the DBT acquisition angle is considered to be one of the most important parameters. The aim of this study was to use texture analysis to assess how the DBT acquisition angle might influence DBT images of breast parenchyma. Methods: Thirty-four patients were selected from a clinical study conducted at IRST Institute. Each patient underwent a dual DBT scan performed with Fujifilm Amulet Innovality (Fujifilm Corp, Tokyo, Japan) in standard (ST, angular range = 15°) and high-resolution (HR, angular range = 40°) modalities. Texture analysis was applied on the paired dataset using histogram-based features and gray level co-occurrence matrix (GLCM) features. Wilcoxon-signed rank and Pearson-rank tests were used to assess the statistical differences and correlations between extracted features. Results: The DBT acquisition angle did not affect histogram-based features, whereas there was a significant difference in five GLCM features (p < 0.05) between DBT images generated with 15° and 40° acquisition angles. Correlation analysis showed that two GLCM features were not correlated at a p < 0.05 significance level. Conclusions: DBT acquisition angle affects the textures extracted from DBT images and this dependence should be considered when establishing baselines for classifiers of malignant tissue. Furthermore, texture analysis could be proposed as a quantitative method for comparing and scoring the contrast of DBT images.