Inicio  /  Cancers  /  Vol: 14 Par: 21 (2022)  /  Artículo
ARTÍCULO
TITULO

Classic and New Markers in Diagnostics and Classification of Breast Cancer

Roman Benacka    
Daniela Szabóová    
Zuzana Gula?ová    
Zdenka Hertelyová and Jozef Radonák    

Resumen

With ever-increasing incidence, breast cancer is considered a most diagnosed type of cancer among women worldwide. Breast cancer arises through malignant transformation of ductal or lobular cells in female (or male) breast and the genetic, phenotypic and morphological heterogeneity has an effect on tumour?s behaviour, thereby instigating a need for individual personalized therapy. A traditional assessment of tumour?s characteristics involves a biopsy and histological analysis of a tumour tissue, and in recent years has been accompanied by analysis of molecular biomarkers to enhance the results. In this work we aimed to thoroughly investigate the latest data in this field of study and give a comprehensive review of novel molecular biomarkers of breast cancer and methodologies used to analyse them.

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