Inicio  /  Cancers  /  Vol: 13 Par: 6 (2021)  /  Artículo
ARTÍCULO
TITULO

Electrochemical Sensing in 3D Cell Culture Models: New Tools for Developing Better Cancer Diagnostics and Treatments

Micaela Oliveira    
Pedro Conceição    
Krishna Kant    
Alar Ainla and Lorena Diéguez    

Resumen

Over the last few years, there has been a scientific revolution with the appearance of organ-on-a-chip models that overcome the limitations of conventional 2D systems, while reproducing more faithfully the in vivo features of tissues and organs. The integration of sensors in these systems allows the monitoring of a variety of parameters that could be relevant for the study of diseases. Electrochemical biosensors are ideal candidates for this integration, since they can be miniaturised and are very reliable in real-time continuous measurements of a large panoply of relevant biomarkers. In the context of cancer, these electrochemical cancer-on-a-chip models have the potential to become essential tools for the study of cancer development and drug efficacy.

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