Resumen
MiR-155 appears to be a significant regulator of immune responses against tumors. The aim of this review is to provide an overview of miR-155 function in distinct immune cell populations and describe how the miR-155-mediated regulation can impact the process of cancer immunoediting. Since miR-155 does not necessarily act only within a single cell, we also touch on the role of miR-155 in cellular communication. Finally, we discuss current developments in the specific targeting of this molecule in the tumor and immune cells and suggest its potential implications in developing novel therapeutic algorithms to increase the efficacy of cancer therapy.