Resumen
Tau protein is a microtubule-associated protein, widely known for its role in neurodegenerative diseases. Recent studies show that Tau can also be involved in the progression of many cancers as well as in cancer treatment resistance. This work overviews the role of Tau in tumorigenic processes with a focus on glioblastoma which exhibits a high expression level of this protein. Unraveling the role of Tau in glioblastoma and cancers, in general, will boost our understanding of the Tau protein and more significantly may open new avenues of strategies for curing cancer patients, in particular those with glioblastoma.