Inicio  /  Cancers  /  Vol: 14 Par: 21 (2022)  /  Artículo
ARTÍCULO
TITULO

Long Non-Coding RNA and microRNA Interplay in Colorectal Cancer and Their Effect on the Tumor Microenvironment

Marie Rajtmajerová    
Andriy Trailin    
Václav Li?ka    
Kari Hemminki and Filip Ambrozkiewicz    

Resumen

The interplay between the tumour and the immune system plays a vital role in disease progression. There are several mechanisms the tumour imposes to repress the immune response. Dysregulation of non-coding RNAs, the main role of which is to regulate transcription and translation, leads to expressional changes in various signaling molecules and can subsequently affect infiltration and/or activation of immune cells. Here, we focus on the miRNA/lncRNA/protein regulatory axes, which are known to influence the immune response in colorectal cancer.

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