Inicio  /  Cancers  /  Vol: 13 Par: 6 (2021)  /  Artículo
ARTÍCULO
TITULO

Cancer and Aging: Two Tightly Interconnected Biological Processes

Lieze Berben    
Giuseppe Floris    
Hans Wildiers and Sigrid Hatse    

Resumen

As life expectancy is increasing, the older population is rapidly growing. However, older patients with cancer are still underrepresented in clinical trials, making treatment of these patients challenging for oncologists. Robust biomarkers that reflect the body?s biological age can be helpful to provide older patients with cancer with an optimal personalized treatment. However, to be able to identify such biomarkers, more in-depth research is needed in this underexplored population. In this review, we have put together the current knowledge concerning the mechanistic connections between aging and cancer, as well as aging biomarkers that could be useful in the field of geriatric oncology.

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