Inicio  /  Cancers  /  Vol: 16 Par: 1 (2024)  /  Artículo
ARTÍCULO
TITULO

Short-Term Outcomes after D2 Gastrectomy with Complete Mesogastric Excision in Patients with Locally Advanced Gastric Cancer: A Systematic Review and Meta-Analysis of High-Quality Studies

Stefano Granieri    
Annaclara Sileo    
Michele Altomare    
Simone Frassini    
Elson Gjoni    
Alessandro Germini    
Alessandro Bonomi    
Eigo Akimoto    
Chun Lam Wong and Christian Cotsoglou    

Resumen

Local recurrence is a significant issue for advanced gastric cancer patients. Complete mesogastric excision (CME) has been advocated to enhance lymph node (LN) retrieval and reduce recurrence rates. A systematic review of the literature was conducted according to the Cochrane recommendations, and meta-analyses of means and binary outcomes were developed. The number of lymph nodes retrieved was the primary endpoint, with other postoperative outcomes as secondary. Thirteen studies were included, showing that the mean number of harvested LNs was significantly higher among patients undergoing CME. CME patients also had significantly lower intraoperative blood loss, a shorter length of stay, and a shorter operative time. Radical gastrectomy with CME may provide a safe and more radical lymphadenectomy. Long-term outcomes and the applicability of this technique in the West are still to be proven.

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