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Inicio  /  Cancers  /  Vol: 16 Par: 1 (2024)  /  Artículo
ARTÍCULO
TITULO

Low Alanine Aminotransferase as a Marker for Sarcopenia and Frailty, Is Associated with Decreased Survival of Bladder Cancer Patients and Survivors?A Retrospective Data Analysis of 3075 Patients

Menachem Laufer    
Maxim Perelman    
Gad Segal    
Michal Sarfaty and Edward Itelman    

Resumen

This article describes the results of a study that checked the association between low levels of ALT (an enzyme) in the blood and the outcomes of patients suffering from bladder cancer. Low ALT blood concentrations are known to be associated with a low, whole-body muscle mass. This state is defined as ?sarcopenia? and is associated with frailty and worse outcomes. Indeed, we found that low ALT levels were associated with shortened survival. This finding is important for physicians when they plan the treatment for their patients. It is assumed that frail patients might experience worse results from aggressive management. This approach is called ?personalized medicine?.

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