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Inicio  /  Cancers  /  Vol: 13 Par: 6 (2021)  /  Artículo
ARTÍCULO
TITULO

Three-Dimensional Radiological Assessment of Ablative Margins in Hepatocellular Carcinoma: Pilot Study of Overlay Fused CT/MRI Imaging with Automatic Registration

Yasunori Minami    
Tomohiro Minami    
Kazuomi Ueshima    
Yukinobu Yagyu    
Masakatsu Tsurusaki    
Takuya Okada    
Masatoshi Hori    
Masatoshi Kudo and Takamichi Murakami    

Resumen

Recent advances in fusion imaging technology have made it easier to visualize and estimate ablative margins. This study was conducted to assess the clinical feasibility of a computed tomography (CT)/magnetic resonance imaging (MRI) fusion application for evaluation of the ablative margin in radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). Seventeen patients developed local tumor progressions (LTPs) due to wrong initial evaluations of technical success through a side-by-side comparison, and we reevaluated the ablative margins using the CT/MRI overlay fusion application. Eight patients were categorized into grade C (margin-zero ablation) and nine patients into grade D (existence of residual HCC). LTP occurred in re-graded C patients within 4 to 30.3 months (median, 14.3 months), and in re-graded D patients within 2.4 to 6.7 months (median, 4.2 months) (p = 0.006). Overlay fused CT/MRI imaging can allow us to evaluate HCC ablative margin three-dimensionally with high accuracy.

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