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Inicio  /  Cancers  /  Vol: 16 Par: 1 (2024)  /  Artículo
ARTÍCULO
TITULO

Comparing Methods to Determine Complete Response to Chemoradiation in Patients with Locally Advanced Cervical Cancer

Kim van Kol    
Renée Ebisch    
Maaike Beugeling    
Jeltsje Cnossen    
Joost Nederend    
Dennis van Hamont    
Sjors Coppus    
Jurgen Piek and Ruud Bekkers    

Resumen

In patients with locally advanced cervical cancer, there is still a high reported locoregional recurrence rate after chemoradiation therapy. Therefore, timely detection of locoregional residual disease is important for patients to be treated with salvage surgery. Furthermore, it is important to select only the patients who would benefit from salvage surgery and not to expose patients unnecessarily to the risks of surgery. Therefore, the aim of this study is to assess two different imaging techniques, MRI and 18F[FDG]-PET/CT, for their ability to determine the presence of locoregional residual disease after chemoradiotherapy in patients with locally advanced cervical cancer. MRI and 18F[FDG]-PET/CT were compared with pathology-proven locoregional residual disease or locoregional recurrence identified from biopsy and/or salvage surgery. The findings from this research provide insights into the ability of MRI and 18F[FDG]-PET/CT to detect locoregional residual disease.

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